2008年4月5日星期六

Smokers at Increased Risk of Aneurysm Recurrence


FRIDAY, March 28 (HealthDay News) -- Smokers with a brain
aneurysm who are treated with coil embolization are more likely than other
patients to develop another aneurysm, according to a U.S. study.



If a brain aneurysm bursts, the bleeding vessel causes a stroke.



During coil embolization, a catheter is inserted into an artery in the
groin and then threaded to the affected area of the brain. One or more
tiny coils are fed through the catheter and placed in the aneurysm. The
body forms a blood clot around the coil, which blocks the aneurysm.



Neurological surgeons at Jefferson Hospital for Neuroscience in
Philadelphia reviewed patient records from 2003 and found that cigarette
smokers -- especially those with low-grade subarrachnoid hemorrhage -- who
received this treatment were at increased risk for aneurysm recanalization
(re-opening). The amount of cigarettes smoked affected the level of
risk.



The researchers found no correlation between increased risk and
aneurysm location and size, type of coil, or coil compaction.



The study -- believed to be the first to document a link between
aneurysm recurrence and smoking -- was published in the April issue of
the Journal of Neurosurgery.



"Of the various factors that lead to a predisposition for these
cerebral aneurysms, cigarette smoking is the only factor that has
consistently been identified in all the populations studied and is also
the most easily preventable," Dr. Erol Veznedaroglu, an associate
professor of neurological surgery and director of the division of
neurovascular surgery and endovascular neurosurgery at Jefferson Medical
College, said in a prepared statement.



The study authors noted that previous research had established a direct
link between cigarette smoking and increased risk of brain aneurysm
formation and growth, but "despite this evidence, more than one third of
prior smokers continue to use nicotine after suffering an aneurysm,
especially patients who started smoking at a young age and those with a
history of depression or alcohol abuse."



While this study didn%26#39;t find a significant association between smoking
cessation and aneurysm recurrence, Veznedaroglu said "patients with known
cerebral aneurysms should be aggressively counseled about the risk of
cigarette smoking."



More information



The Brain Aneurysm Foundation has more about treatment
options.

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